Job Details
Job Location
Torrance Campus - Torrance, CA
Position Type
FT 100% - 40 hours per week (FT Benefit)
Salary Range
$68640.00 - $70000.00 Salary/year
Description
The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (TLI) advances medical science by focusing on research that addresses real-world needs. We have an exciting opportunity for a Postdoctoral Scientist to join Dr. Michelle Matter’s research team at TLI in Torrance, California. The Matter lab investigates the molecular and cellular mechanisms that govern adhesion mediated cell survival and metabolism. In particular, the lab focuses on the emerging concept of the role of the extracellular matrix in pro-survival signaling and mitochondrial homeostasis and how that relates to disease.
The Postdoctoral Scientist will dissect the molecular basis of a pro-survival gene that protects the heart from the mechanical stresses of pregnancy induced hypertrophy. They will use our heart-specific knock out mice, in vitro and in vivo assays, and mechchanotransduction assays to investigate the mechanistic basis of protein-protein interactions that regulate cardiomyocyte survival. This project will use a multi- disciplinary approach that integrates biochemistry, biophysics and cell biology techniques, combined with integrin-mediated mechanotransduction to understand pro-survival signaling in the heart.
This opportunity is for an engaged, creative, and collaborative scientist who will bring their enthusiasm for scientific discovery and developing innovative methodologies into the lab. The ideal candidate is highly collaborative, demonstrates strong communication and computer skills, and is committed to professional growth and development.
What TLI provides: - Collaborative lab environment focused on discovery, innovation, creativity, and scientific rigor. - A vibrant TLI research community with weekly research seminars and professional development - courses. - Scientific mentorship. - Opportunities to mentor the next generation of scientists. - Encourages attendance at scientific workshops and conferences. - Competitive compensation package with comprehensive health and wellness benefits. • - What the qualified Postdoctoral Scientist will do: - Lead a research project focusing on protein biochemistry including cell fractionation, organelle and protein purification, fluorescent microscopy, cell biology, and mechanotransduction assays to understand the molecular basis of cardiomyocyte survival under stress conditions. - Develop new experimental approaches to advance the project and the lab’s research efforts. - Write scientific manuscripts describing research findings. - Attend local and national meetings to present research findings, learn about the latest advances in - the field, and develop a scientific network.
Qualifications: - PhD in the life sciences is required. Focus on protein biochemistry, cardiomyocyte biology or integrin-mediated signaling is preferred. - Experience with the Lagendorff heart system for isolating mouse primary cardiomyocytes is a plus. - Strong publication record, including at least one first author paper either published or in pre-print form from your PhD studies. - Excellent communication skills with the ability to present and discuss findings. - Willingness to learn new techniques, share expertise, and contribute to the collective success of the team. - Excellent organizational and time management skills.